This is a simple, but useful one. If you hate ADs as much as I do, this is a quick solution that gets rid of most of the advertisements in the Apple News app on the Mac.
All you have to do is add/modify a line in your /etc/hosts
and send traffic for news.iadsdk.apple.com
into the bit bucket:
127.0.0.1 localhost news.iadsdk.apple.com
If you have access to a squid server, you can have it block the same and send your iOS traffic through that proxy to have the same effect on your iPhone and iPad.